SCID (TREC & KREC)
Detection of TREC & KREC levels by Loop-mediated isothermal amplification.
The LAMP Human SCID detection KIT is an in vitro diagnostic KIT as primary screening method for the detection of SCID by Loop-mediated isothermal amplification (LAMP). This assay is dedicated to professional use in diagnostic laboratory. The device is not for self-testing.
Severe Combined Immunodeficiency Disease (SCID) is a condition in which there are no or abnormally low levels of T cells and/or low, high or normal numbers of B cells and NK cells. The prevalence is 1/50-100,000 newborns. In the absence of treatment, early signs of the disease begin to appear during the first few months of life and may include :
Babies with SCID are protected by their mother's immune system for a short period of time after birth. Neonatal screening for SCID before symptoms appear makes it possible to perform a bone marrow transplant and thus save the newborn.
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