Factor II (Prothrombin) mutation
The LAMP Human Prothrombin mutation KIT is an in vitro diagnostic test intended for the qualitative detection of Factor II G20210A by Loop-mediated isothermal amplification (LAMP) on EDTA whole blood and extracted DNA. This assay is dedicated to professional use in diagnostic laboratories. The device is not for self-testing.
Factor II (prothrombin) gene mutation is one of the primary genetic causes for inherited thrombophilia, a blood coagulation disorder that increases the risk for venous thromboembolism (VTE).
Factor II mutation c.*97G>A (G20210A or 20210G>A) is located in the gene promotor region and is associated with elevated plasma levels of prothrombin, resulting in an increased risk of blood clot formation. The Allele Frequency of the mutated allele is around 2% in the Caucasian population.
Format: 24 or 96 determinations
Storage: At -20°C. 8 freeze and thaw max.
Possible automation: Yes
Analysis software : Yes
Turn around time: Around 1 hour
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