LAMP HUMAN PAI-1 MUTATION KIT

Detection of the 4G/5G Plasminogen Activator Inhibitor-1 mutation

Format References
24 reactions LC-PAI1-LP-24



INTENDED USE

The LAMP Human PAI-1 mutation KIT is an in vitro diagnostic test. This assay is dedicated to professional use in diagnostic laboratory. The device is not for self-testing.


DISEASE INFORMATION

Plasminogen activator inhibitor-1 (PAI-1) belongs to the serine protease superfamily. It is a primary regulator of plasminogen activation. A common single nucleotide insertion/deletion in the promotor region of the PAI-1 gene has been identified and is related to circulation PAI-1 concentrations, whereby the 4G allele shows highest PAI-1 concentrations.